Phase I Projects

SLAC-led projects

Closed-Loop Autonomous Discovery of Mechanistic Activity-Selectivity-Stability Rules in Catalysis

Lead institution: SLAC National Accelerator Laboratory

Partner institutions: California Institute of Technology, Lawrence Berkeley National Laboratory

A Multi-Agent AI Framework for Discovering Chemical Drivers of Selective Critical Metal Recovery from Complex Battery Waste

Lead institution: SLAC National Accelerator Laboratory

Partner institution: University of Southern California

SLAC collaboration projects

From Beam Loss to Beam Intelligence: Adaptive Generative AI for Autonomous Accelerator Facilities

Lead institution: Los Alamos National Laboratory

Digital Twins for Laser-Plasma Wakefield Acceleration: From Plasma Channel Formation to Beam Optimization

Lead institution: Lawrence Livermore National Laboratory

CMOS + X: AI-Enabled Cross-Domain Co-Design for Low-Temperature Electronics, Sensors and Computation

Lead institution: Argonne National Laboratory

Structural dynamics enable enzyme design for useful biotechnology

Lead institution: University of California, San Francisco

Toward a U.S. Institute for Cell Design: AI-Driven Computer-Ready Synthetic Cells with Quantum Integration

Lead institution: University of Missouri

High-throughput edge AI for real-time, multi-task inference on high-bandwidth plasma fluctuation diagnostics: a transformative enabling technology for fusion energy

Lead institution: University of Wisconsin-Madison

AI/ML Resonance control for high-reliability, low-cost accelerator operations

Lead institution: Fermi National Accelerator Laboratory

A Unified Multimodal Data Service for AI-Driven Cosmology

Lead institution: Carnegie Mellon University

ORACLE: Observatory for Reasoning, Anomaly detection, and Causal Learning in Experiments

Lead institution: Stanford University

Mixture-of-Experts Foundation Models for Scalable Holistic Reconstruction, Modeling, and Interpretation of Particle Interactions

Lead institution: College of William and Mary

Developing a Foundation Model to Unify Neutrinoless Double Beta Decay Search Technologies

Lead institution: University of Hawaii